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Increased urinary urate

MedGen UID:
168055
•Concept ID:
C0878672
•
Finding

Professional guidelines

PubMed

Controlled inpatient study of tienilic acid in treatment of gout and hypertension.
Reardon JA, Scott JT
Ann Rheum Dis 1980 Aug;39(4):367-72. doi: 10.1136/ard.39.4.367. PMID: 7436563Free PMC Article

Recent clinical studies

Etiology

Protection of curcumin against fructose-induced hyperuricaemia and renal endothelial dysfunction involves NO-mediated JAK-STAT signalling in rats.
Zhang DM, Li YC, Xu D, Ding XQ, Kong LD
Food Chem 2012 Oct 15;134(4):2184-93. Epub 2012 Apr 17 doi: 10.1016/j.foodchem.2012.04.026. PMID: 23442673
Plasma urate in diabetes: relationship to glycaemia, glucose disposal, microvascular complications and the variations following oral glucose.
Olukoga AO, Erasmus RT, Akinlade KS, Okesina AB, Alanamu AA, Abu EA
Diabetes Res Clin Pract 1991 Nov;14(2):99-105. doi: 10.1016/0168-8227(91)90115-t. PMID: 1756687

Diagnosis

Effects of renal function on pharmacokinetics and pharmacodynamics of lesinurad in adult volunteers.
Gillen M, Valdez S, Zhou D, Kerr B, Lee CA, Shen Z
Drug Des Devel Ther 2016;10:3555-3562. Epub 2016 Nov 1 doi: 10.2147/DDDT.S119944. PMID: 27843295Free PMC Article
Plasma urate in diabetes: relationship to glycaemia, glucose disposal, microvascular complications and the variations following oral glucose.
Olukoga AO, Erasmus RT, Akinlade KS, Okesina AB, Alanamu AA, Abu EA
Diabetes Res Clin Pract 1991 Nov;14(2):99-105. doi: 10.1016/0168-8227(91)90115-t. PMID: 1756687

Therapy

Effects of renal function on pharmacokinetics and pharmacodynamics of lesinurad in adult volunteers.
Gillen M, Valdez S, Zhou D, Kerr B, Lee CA, Shen Z
Drug Des Devel Ther 2016;10:3555-3562. Epub 2016 Nov 1 doi: 10.2147/DDDT.S119944. PMID: 27843295Free PMC Article
Fructus Gardenia Extract ameliorates oxonate-induced hyperuricemia with renal dysfunction in mice by regulating organic ion transporters and mOIT3.
Hu QH, Zhu JX, Ji J, Wei LL, Miao MX, Ji H
Molecules 2013 Jul 29;18(8):8976-93. doi: 10.3390/molecules18088976. PMID: 23899832Free PMC Article
Protection of curcumin against fructose-induced hyperuricaemia and renal endothelial dysfunction involves NO-mediated JAK-STAT signalling in rats.
Zhang DM, Li YC, Xu D, Ding XQ, Kong LD
Food Chem 2012 Oct 15;134(4):2184-93. Epub 2012 Apr 17 doi: 10.1016/j.foodchem.2012.04.026. PMID: 23442673
Controlled inpatient study of tienilic acid in treatment of gout and hypertension.
Reardon JA, Scott JT
Ann Rheum Dis 1980 Aug;39(4):367-72. doi: 10.1136/ard.39.4.367. PMID: 7436563Free PMC Article

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